Modeling the efficiency of filovirus entry into cells in vitro: Effects of SNP mutations in the receptor molecule.

Interaction between filovirus glycoprotein (GP) and the Niemann-Pick C1 (NPC1) protein is essential for membrane fusion during virus entry.Some single-nucleotide polymorphism (SNPs) in two surface-exposed loops of NPC1 are known to reduce viral infectivity.However, the dependence of differences in Travel Essentials entry efficiency on SNPs remains

read more


Assessment of Embedded Conjugated Polymer Sensor Arrays for Potential Load Transmission Measurement in Orthopaedic Implants

Load transfer through orthopaedic joint implants is poorly understood.The longer-term outcomes of these implants are just starting to be studied, making it imperative to monitor contact loads across the entire joint implant interface to elucidate the force transmission and distribution mechanisms exhibited by these implants in service.This study pr

read more

Study on the correlation of supplementation with L-citrulline on the gastrointestinal flora and semen antifreeze performance of ram

IntroductionCryopreservation of semen can give full play to the reproductive advantages of male animals.However, in actual production, due to the poor frost resistance of sheep semen and the low conception rate, the promotion of sheep frozen semen is greatly hindered.Therefore, it is urgent to improve the frost resistance of semen to improve the qu

read more